Hewlett Packard Enterprise 838081-B21 Memory Module

The Hewlett Packard Enterprise 838081-B21 memory module is a 16GB DDR4 RDIMM designed for HPE ProLiant Gen10 servers, delivering increased memory capacity and ECC-protected reliability for enterprise workloads. This 288-pin, single-rank (1Rx4) DIMM operates at 1.2V and runs DDR4-2666V (PC4-21300) with ECC, providing data integrity for virtualization, databases, and cloud infrastructure. Commonly installed in rack and blade servers, virtualization hosts, and storage platforms, it supports memory upgrades, failed-DIMM replacement, capacity expansion, and restoring stable operation in business-critical environments. It is identified by Manufacturer Part Number 838081-B21, with Spare 868842-001 and Assembly/Option 840757-191, and is part of HPE's enterprise memory lineup for Gen10 platforms. Common replacements include HPE 805349-B21, P07642-B21, and 726718-B21, reflecting compatibility across HPE memory upgrade paths. Applications span enterprise data centers, virtualization clusters, and cloud deployments requiring dependable ECC memory to improve multitasking and data processing performance.